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恭喜王丰博士,杨浩东硕士的研究成果被Angewandte Chemie接收!

Dec 12, 2018


Silver‐Promoted Oxidative Benzylic C−H Trifluoromethoxylation
https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201807144

Abstract: A silver‐promoted oxidative benzylic C−H trifluoromethoxylation has been reported for the first time. With trifluoromethyl arylsulfonate as the trifluoromethoxylation reagent, various arenes, having diverse functional groups, undergo trifluoromethoxylation of their benzylic C−H bonds to form trifluoromethyl ethers under mild reaction conditions. In addition, the trifluoromethoxylation and the fluorination of methyl groups of electron‐rich arenes have been achieved to prepare α‐fluorobenzyl trifluoromethyl ethers in one step.